Juxtaglomerular apparatus is a special sensitive region formed by cellular modifications in the:
1. DCT and Efferent arteriole at the point of their contact
2. DCT and the Afferent arteriole at the point of their contact
3. PCT and Afferent arteriole at the point of their contact
4. PCT and Efferent arteriole at the point of their contact
Regarding the control of water balance by the kidneys:
1. | The renal medulla has an osmotic gradient that decreases from the border with the cortex to the renal papilla. |
2. | ADH is secreted by anterior pituitary in response to a decrease in the osmolality of the blood. |
3. | A normal person cannot produce urine with an osmolality greater than 300 mOsmil.kg-1. |
4. | ADH acts on the cells of the collecting ducts to increase their permeability to water. |